Friday, January 24, 2020

GENE THERAPY :: essays research papers

Many diseases seen today are the result of a defective gene in the DNA of the patient and can not be cured using the traditional methods such as antibiotics and antiviral medication. The victims are now looking to gene therapy as a potential cure for their problems. Bob Williamson introduces us the concept, procedures, and problems associated with gene therapy in his article,  ¡Ã‚ °Gene Therapy ¡Ã‚ ±. Along with the appearance of the recombinant DNA technology, it becomes possible for human beings to isolate, study, and change gene in the laboratory. Gene Therapy is the process of replacing a defective gene inside a patient ¡Ã‚ ¯s DNA with a working gene that will produce the correct gene products. The genetic diseases  ¡Ã‚ °in which a single known gene does not function properly ¡Ã‚ ±, such as sickle cell anaemia, thalassaemia and Lesch-Nyhan syndrome, are most suitable to be treated with the gene therapy. There are two types of gene therapy in curing these diseases, patient therapy and embryo therapy. In the process of the patient therapy, the first step is identifying the defective gene and isolating a normal counterpart.  ¡Ã‚ ° To obtain correct gene action, it may be necessary to put it into the correct site on the host cell chromosome, or even to delete the defective gene ¡Ã‚ ±, and the DNA can then be replicated each time the host cell divided. But if the new cell is injected directly into the patient ¡Ã‚ ¯s body, it will be subject to the body ¡Ã‚ ¯s immune system that will recognize it as foreign and target it to be destroyed along with the healthy DNA that it is carrying. So the cells extracted from the patient are to be treated and adding the new gene in a test tube in the laboratory to make sure that the DNA is inserted in an appropriate place in the genome, and the cells can then be returned to the patient ¡Ã‚ ¯s body.   Ã‚  Ã‚  Ã‚  Ã‚  Now it is possible to offer the parents an antenatal diagnosis to look over if the fetus is affected by some single gene defects. If it does, the parents can choose embryo therapy to cure it rather then abortion. While the basic process is similar with the one of patient therapy, to do an embryo therapy is a little bit easier than a patient therapy, because the immune rejection system of the embryo is not fully developed. The new DNA will not be ejected, while the former DNA will be altered.

GENE THERAPY :: essays research papers

Many diseases seen today are the result of a defective gene in the DNA of the patient and can not be cured using the traditional methods such as antibiotics and antiviral medication. The victims are now looking to gene therapy as a potential cure for their problems. Bob Williamson introduces us the concept, procedures, and problems associated with gene therapy in his article,  ¡Ã‚ °Gene Therapy ¡Ã‚ ±. Along with the appearance of the recombinant DNA technology, it becomes possible for human beings to isolate, study, and change gene in the laboratory. Gene Therapy is the process of replacing a defective gene inside a patient ¡Ã‚ ¯s DNA with a working gene that will produce the correct gene products. The genetic diseases  ¡Ã‚ °in which a single known gene does not function properly ¡Ã‚ ±, such as sickle cell anaemia, thalassaemia and Lesch-Nyhan syndrome, are most suitable to be treated with the gene therapy. There are two types of gene therapy in curing these diseases, patient therapy and embryo therapy. In the process of the patient therapy, the first step is identifying the defective gene and isolating a normal counterpart.  ¡Ã‚ ° To obtain correct gene action, it may be necessary to put it into the correct site on the host cell chromosome, or even to delete the defective gene ¡Ã‚ ±, and the DNA can then be replicated each time the host cell divided. But if the new cell is injected directly into the patient ¡Ã‚ ¯s body, it will be subject to the body ¡Ã‚ ¯s immune system that will recognize it as foreign and target it to be destroyed along with the healthy DNA that it is carrying. So the cells extracted from the patient are to be treated and adding the new gene in a test tube in the laboratory to make sure that the DNA is inserted in an appropriate place in the genome, and the cells can then be returned to the patient ¡Ã‚ ¯s body.   Ã‚  Ã‚  Ã‚  Ã‚  Now it is possible to offer the parents an antenatal diagnosis to look over if the fetus is affected by some single gene defects. If it does, the parents can choose embryo therapy to cure it rather then abortion. While the basic process is similar with the one of patient therapy, to do an embryo therapy is a little bit easier than a patient therapy, because the immune rejection system of the embryo is not fully developed. The new DNA will not be ejected, while the former DNA will be altered.

GENE THERAPY :: essays research papers

Many diseases seen today are the result of a defective gene in the DNA of the patient and can not be cured using the traditional methods such as antibiotics and antiviral medication. The victims are now looking to gene therapy as a potential cure for their problems. Bob Williamson introduces us the concept, procedures, and problems associated with gene therapy in his article,  ¡Ã‚ °Gene Therapy ¡Ã‚ ±. Along with the appearance of the recombinant DNA technology, it becomes possible for human beings to isolate, study, and change gene in the laboratory. Gene Therapy is the process of replacing a defective gene inside a patient ¡Ã‚ ¯s DNA with a working gene that will produce the correct gene products. The genetic diseases  ¡Ã‚ °in which a single known gene does not function properly ¡Ã‚ ±, such as sickle cell anaemia, thalassaemia and Lesch-Nyhan syndrome, are most suitable to be treated with the gene therapy. There are two types of gene therapy in curing these diseases, patient therapy and embryo therapy. In the process of the patient therapy, the first step is identifying the defective gene and isolating a normal counterpart.  ¡Ã‚ ° To obtain correct gene action, it may be necessary to put it into the correct site on the host cell chromosome, or even to delete the defective gene ¡Ã‚ ±, and the DNA can then be replicated each time the host cell divided. But if the new cell is injected directly into the patient ¡Ã‚ ¯s body, it will be subject to the body ¡Ã‚ ¯s immune system that will recognize it as foreign and target it to be destroyed along with the healthy DNA that it is carrying. So the cells extracted from the patient are to be treated and adding the new gene in a test tube in the laboratory to make sure that the DNA is inserted in an appropriate place in the genome, and the cells can then be returned to the patient ¡Ã‚ ¯s body.   Ã‚  Ã‚  Ã‚  Ã‚  Now it is possible to offer the parents an antenatal diagnosis to look over if the fetus is affected by some single gene defects. If it does, the parents can choose embryo therapy to cure it rather then abortion. While the basic process is similar with the one of patient therapy, to do an embryo therapy is a little bit easier than a patient therapy, because the immune rejection system of the embryo is not fully developed. The new DNA will not be ejected, while the former DNA will be altered.

Thursday, January 16, 2020

Ptlls 008 Roles, Responsibilities Essay

Important to define the terms prior to listing the entities which may impact on my work: Legislative requirement: A duty to act according to the law as defined in an Act of Parliament and usually enforceable through the courts. Code of Practice: A set of rules outlining how a person in a particular profession or situation is expected to behave. Statutory Code of Practice: A Code of Practice approved by Parliament and admissible as evidence in any legal action. The Children Act (2004) – Every Child Matters underpinned the Change For Children agenda. The Act came into being following the death of Victoria Climbie. The Act is applicable to children and vulnerable adults up to the age of 25. Focused on five specific outcomes for children: Be healthy Stay Safe Enjoy and Achieve Make a positive contribution Achieve economic well-being Protection of Children Act (1991) – gave local authorities to investigates cases of child abuse. Safeguarding Vulnerable Groups Act (2006) – introduced a vetting and barring service for those working with children and vulnerable adults. Disclosure and Barring Service (DBS) checks (previously CRB checks). Code of Professional Practice (2008) – introduced by the Lifelong Learning Sector. The code is based on 7 behaviours expected of teachers. Copyright Designs and Patents Act (1988) – relates to copying and adapting materials. The Data Protection (1998) – relates to information held on people by others. Education and Skills Act (2008) – aimed at increasing participation in learning. The Equality Act (2010) – brought all the areas of discrimination: race, sex, disability, race into one Act. The 2010 Act identifies 9 areas of discrimination. Freedom Of Information Act (2000) – individuals can ask to see the information held on them Health and Safety At Work (1974) – imposes obligations on all to operate within a safe and healthy environment Human Rights Act (1998) – basic rights for all The Further Education Teacher’s Qualifications (England) Regulations (2007) – professional status for teachers in FE and a qualification route GRAVELLS, A. (2012) Preparing To Teach In The Lifelong Learning Sector 1. 2 Analyse own responsibilities for promoting equality and valuing diversity The definition of equality is to treat everybody equally, especially in terms of status, rights and opportunities. The 2010 Equality Act brought together a number of different pieces of legislation which means it is unlawful to discriminate against people on the grounds of pay, sex, race and disability. Diversity means being aware that every person is unique, not only because of their visible differences such as race, age or disability, but also non visible differences, religion, social background, economic status or political beliefs. Inclusion is about being objective and looking beyond first impressions. It’s about diversity and breaking down barriers, changing lives and promoting equality. Within my role it’s important for me to base my practice around the concepts of equality, diversity and inclusion and keep an open mind. Without an open mind I may not support all people equally to recognise their potential and achieve their aspirations. Discrimination could then be argued to have occurred as students would not have been treated equally. Particular to my role as a potential facilitator would be the areas of Differentiation Preconceived stereotypes Encouraging a wide variety of views Use of culturally diverse images and resources Learning support where appropriate 1. 3 Evaluate own role and responsibilities in lifelong learning Reflective Journal Annex A It is important to consider this question in relation to internal and external influences. My role as a facilitator is connected to the Learning Cycle. The cycle consists of five reoccurring elements. It is appropriate for me to answer this question offering examples for each element. Identify needs. Role – arranging assessments to identify student need particularly in the key skill areas: numeracy, literacy and ICT Responsibility – offering information, advice and guidance on the contents of the course Plan learning Role – planning schemes of work and when it will be taught Responsibility – designing a scheme of work, lesson plans and resources Deliver/Facilitate learning Role – establish ground rules Responsibility – deal with inappropriate behaviour as it arises Assessing Learning Role – assess progress whether it be for internal purposes or national examination bodies Responsibility – offering feedback to students Evaluation Role – improve the teaching and learning process Responsibility – evaluate session taught perhaps through student reflective journals 1. 4 Review own role and responsibilities in identifying and meeting the needs of learner Reflective Journal Annex B To meet the needs of the learner, firstly I would conduct an initial assessment, particularly in the areas of key skills: literacy, numeracy and ICT. This would enable both myself and the learner to identify and agree areas where additional support was required to enhance learning Secondly I would negotiate Individual Learning Plans (ILPs) to enable both the learner and myself to set targets and monitor outcomes. Thirdly I would initiate regular tutorials where individuals could receive dedicated individual attention where achievement could be celebrated and support and help offered. Lastly, I would constantly be mindful of barriers to learning whether this be learning or personal ones. In such cases where there were issues depending on the nature of these issues I would either deal with them myself or signpost the student to an appropriate professional 2. Understand the relationships between teachers and other professionals in lifelong learning 2. 1 Analyse the boundaries between the teaching role and other professional roles There are three areas on which I intend to focus. First the teachers time is limited it therefore may be appropriate to refer a student to another professional, for example if the students wishes to discuss their career ideas, although I would feel comfortable doing this I may not have the time. I would therefore signpost them to a career expert. Secondly the teacher may not have a particular expertise and teachers should be respectful of the abilities of other professionals. For example if my computer projector broke down I would ask a technician to repair it. They would have both the expertise and health and safety knowledge to complete the task. Thirdly within the busy life of a classroom it is not always possible to meet the specific needs of the learner whether this is in respect of key skills, language barriers or personal problems. In any of the incidents it would be appropriate for me to refer them to another professional. The key is always to support the learning of the learner.

Wednesday, January 8, 2020

Gun Control And Border Security - 2025 Words

Gun control and border security are two of the major problems Texas is facing these days. According to, â€Å"The Texas Political Project†, immigration is the top most problem Texas is facing today while border security is the second. This leads to an increase in other illegalities like drug trafficking, homicides, mafia wars etc. Premature birth, persistent extermination, and the death penalty are all ambiguous issues in today s general public. Gun control is one of the most convoluted and contentious issues in Texas today. The right to bear arms commenced from the minute men and the American Revolution. The second amendment states: A well regulated militia, being necessary to the security of a free State, the right of the people to keep and bear Arms, shall not be infringed. It allows ordinary people to protect themselves and their families from harm. According to statistics, most Americans believe that an average citizen should have the right to own a handgun. 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